Pharmaceutical carrier and compositions
AssigneeSociete d'Assistance Technique pour Produits Nestle S.A.
InventorPierre Hirsbrunner
Life of this patent
Estimating the term…
Abstract
A pharmaceutical carrier or excipient comprises milk solids and tripotassium phosphate. It is especially suitable for preparing compositions containing moisture-sensitive active ingredients, which may also be acidic in character. The carrier is especially suitable for compounding with ASA (acetylsalicylic acid) to give compositions which disperse readily on contact with water. The resulting solutions are buffered and contain neutralized ASA dissolved in a liquid milk phase.
Claims15
A stable, dry ASA (acetylsalicylic acid) composition which on contact with water disperses rapidly to provide a buffered solution of neutralised ASA in a continuous liquid phase containing dissolved milk solids, characterised in that it contains an effective amount of ASA, milk solids in an amount where the weight ratio of the milk solids (expressed on a non-fat basis) to all other ingredients is 3 to 20:1, and tripotassium phosphate in an amount sufficient to neutralise the ASA.
A pharmaceutical carrier or excipient in powder form characterised in that it comprises milk solids and tripotassium phosphate in an amount sufficient to bind moisture associated with the milk solids.
Dependencies are inferred from the claim text.