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US 4,399,125 AGranted
Novel antagonists of the antidiuretic action of arginine vasopressin
OwnerMaurice Manning, Wilbur H. Sawyerinventors
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Abstract
Compounds acting as antagonists of the antidiuretic activity of arginine vasopressin are those of the formula ##STR1## wherein X is D-Phe, D-Val, D-Leu, D-Ile, D-Arg, D-norvaline, D-norleucine, D-cyclohexylalanine, D-.alpha.-aminobutyric acid, D-threonine or D-methionine and Z is D- or L-Arg.
Claims13
A compound of the formula ##STR4## wherein X is D-Phe, D-Val, D-Leu, D-Ile, D-Arg, D-norvaline, D-norleucine, D-cyclohexylalanine, D-.alpha.-aminobutyric acid, D-threonine or D-methionine and Z is D- or L-Arg.
Dependencies are inferred from the claim text.