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US 4,398,030 AGranted
3-[(Substituted-amino)(aryl)methyl]-1H-indoles
AssigneeSterling Drug Inc.
InventorsPaul J. Schmidt, William M. Hung
Life of this patent
Estimating the term…
Abstract
3-[(Substituted-amino)(aryl or heteroaryl)methyl]-1H-indoles which are useful as color-formers in pressure-sensitive carbonless duplicating systems and thermal marking systems are prepared by reacting 3-[(arylsulfonyl)(aryl or heteroaryl)methyl]-1H-indoles with amines or precursors thereof in the presence of a base.
Claims7
A compound having the formula ##STR12## wherein:
- R.sub.1 is hydrogen or lower-alkyl;
- R.sub.2 is hydrogen, lower-alkyl or phenyl;
- R.sub.3 is hydrogen or lower-alkyl;
- R.sub.4 is hydrogen, lower-alkyl, benzyl, di-lower-alkyl-amino-lower-alkyl, tri-lower-alkylammonium-lower-alkyl, phenyl, phenyl substituted with 1 or 2 halo, lower-alkyl or lower-alkoxy groups, or NR.sub.3 R.sub.4 is pyrrolidino, piperidino, hexamethyleneimino or morpholino;
- and
- Z is biphenylyl, naphthyl or a substituent having the formula ##STR13## wherein:
- R.sub.5 and R.sub.6 are independently lower-alkyl or benzyl and
- R.sub.7 is hydrogen, lower-alkyl, lower-alkoxy, halo or di-lower-alkylamino.
5 more elements
A compound according to clam 3 wherein R.sub.4 is lower-alkyl, phenyl or phenyl substituted with 1 or 2 halo groups .
Dependencies are inferred from the claim text.