4-Carboxy-2-acetamido thiazolidine derivatives
AssigneeTaisho Pharmaceutical Co., Ltd.
InventorsSeiichi Takano, Susumu Otomo, Takehiro Amano
Life of this patent
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Abstract
A novel thiazolidine derivative having the following general formula ##STR1## wherein R.sup.1 and R.sup.2 are each lower alkyl having 1 to 3 carbon atoms, or R.sup.1 and R.sup.2 together with the nitrogen atom to which they are attached form a heterocyclic ring selected from the group consisting of morpholino, piperazino, piperidino and pyrrolidino, or said heterocyclic ring substituted with 1 or 2 methyl groups, and the pharmaceutically acceptable salts thereof are useful immunomodulators.
Claims8
A thiazolidine derivative having the following general formula ##STR12## wherein R.sup.1 and R.sup.2 are each lower alkyl having 1 to 3 carbon atoms, or R.sup.1 and R.sup.2 together with the nitrogen atom to which they are attached form a heterocyclic ring selected from the group consisting of morpholino, piperazino, piperidino and pyrrolidino, or said heterocyclic ring substituted with 1 or 2 methyl groups, and the pharmaceutically acceptable salts thereof.
4-carboxy-2,5,5-trimethylthiazolidine-2-N,N-dimethylacetamide.
4-carboxy-2,5,5-trimethylthiazolidine-2-acetopyrrolidide.
4-carboxy-2,5,5-trimethylthiazolidine-2-acetomorpholide.
4-carboxy-2,5,5-trimethylthiazolidine-2-aceto-N-methylpiperazide.
4-carboxy-2,5,5-trimethylthiazolidine-2-aceto-3,5-dimethylpiperidide.
4-carboxy-2,5,5-trimethylthiazolidine-2-acetopiperidide.
4-carboxy-2,5,5-trimethylthiazolidine-2-N,N-diethylacetamide.
Dependencies are inferred from the claim text.