Process for prolonging retention of emulsion particles in the bloodstream
AssigneeUniversity of Pennsylvania
InventorHenry A. Sloviter
Life of this patent
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Abstract
The retention of coated particles previously infused into the bloodstream of animals may be prolonged by one or more injections of coating substance. For example, the retention of an artificial blood composition comprising emulsified lecithin-coated perfluoro compounds may be prolonged by injection of lecithin.
Claims15
A process for prolonging the stability and retention of coated water insoluble oxygen transporting particles infused into the bloodstream of animals and humans comprising at least one subsequent injection of the same substance which coats the infused particles.
A process for prolonging the stability and retention of a perfluoro compound emulsion in the circulation useful as an artificial blood containing about 30-75% (w/v) perfluoro compound and about 7-9% (w/v) lecithin comprising at least one subsequent injection of lecithin into the circulation.
Dependencies are inferred from the claim text.