Isoxazole derivatives
AssigneeYoshitomi Pharmaceutical Industries, Ltd.
InventorsTakeshi Kawakita, Tomio Muro, Michihide Setoguchi
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Abstract
Isoxazole derivatives represented by the formula ##STR1## wherein Ar, R.sup.1, R.sup.2 and Am are as defined in the specification, or salts thereof. These compounds are useful as drugs such as psychotropic agent, antiemetic agent, etc.
Claims10
An isoxazole represented by the formula ##STR7## or salts thereof wherein Ar represents a phenyl group which may optionally be substituted with a halogen atom or a lower alkoxy group, or a pyridyl group, R.sup.1 represents a hydrogen atom, a lower alkyl or a group represented by a group Ar, R.sup.2 represents a hydrogen atom, or alternatively R.sup.1 and R.sup.2 are bound together and form a carbon-carbon bond, and Am represents an amino residue selected from the group consisting of the following residues:
- ##STR8## wherein R.sup.3 represents a hydrogen atom or a lower alkyl group, X.sup.1 and X.sup.2 each represent a hydrogen atom, a halogen atom or a trifluoromethyl group and Y represents O or S.
Dependencies are inferred from the claim text.