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US 4,397,852 AGranted
[3,6-Pyridazinediylbis(thio)]bis-[2,2-dimethylalkanoic acids] and derivatives as anti-arteriosclerotic agents and method
AssigneeWarner-Lambert Company
InventorIla Sircar
Life of this patent
Estimating the term…
Abstract
New substituted [3,6-pyridazinediylbis(thio)]bis-[2,2-dimethylalkanoic acids] and derivatives which are useful as anti-arteriosclerotic agents are disclosed. These compounds elevate the high density lipoprotein fraction of cholesterol, and also lower the low density lipoprotein fraction of cholesterol.
Claims10
A compound having the structural formula ##STR7## wherein n is 3;
- X is hydrogen, phenyl, or alkyl of from 1 to 6 carbon atoms;
- R is hydrogen, alkyl of from 1 to 6 carbon atoms or a pharmaceutically acceptable cation;
- and the pharmaceutically acceptable acid addition salts thereof.
Dimethyl 6,6'-(3,6-pyridazinediylbis(thio)bis(2,2-dimethyl hexanoate) and the pharmaceutically acceptable acid addition salts thereof.
Dependencies are inferred from the claim text.