Contained blood gas control
AssigneeIntensive Technology, Inc.
InventorsAlan H. Runck, G. Joseph Beatrice
Life of this patent
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Abstract
A chemical seal for isolating the liquid phase of a contained liquid from the vapor phase present in the container headspace comprises a chemically impregnated gel formed by mixing a biopolymer gel, a high molecular weight polymer and chemical impregnants with water to form a gel-forming aqueous solution which is applied to the surface of the contained liquid and allowed to solidify thereby forming a mechanically stable, chemically impregnated gel seal in intimate contact with the contained liquid.
Claims19
A process for isolating a contained blood gas control from the remaining headspace in the container comprising partially filling a container with a blood gas control, applying an aqueous polymer gel-forming solution to the surface of the blood gas control thereby partially filling the headspace in the container and allowing the solution to form a mechanically stable, thin but nonporous, plural phase gel seal in intimate contact with the surface of the contained blood that prevents changes in equilibration between the liquid and gaseous phases of the control.
A process for preparing a chemical seal for isolating the gaseous and liquid phases of a contained blood gas control comprising the steps of forming an aqueous solution of a water soluble gel, a water soluble high molecular weight polymer, the gel and polymer each being present in an amount of from 0.5 to 6 percent (weight per volume of solution);
- subjecting the solution to an elevated temperature sufficient to maintain it in a liquid phase until use;
- carefully applying the solution onto the surface of the contained blood gas control to be sealed until that surface is completely covered;
- and allowing the contained blood gas control and solution to cool sufficiently to cause the solution to form a mechanically stable, thin but nonporous, plural phase gel seal in intimate contact with the blood gas control thereby forming a barrier between the blood gas control and the remaining headspace in the container that prevents changes in equilibration between the liquid and gaseous phases of the control.
A contained blood gas control comprising a container, a volume of blood gas control partially filling the container and a chemical seal for said control formed by mixing a water soluble biopolymer gel, a water soluble high molecular weight polymer and one or more selected water soluble blood compatible chemicals in water at an elevated temperature to form an aqueous solution, the gel and polymer each being present in an amount of from 0.5 to 6 percent (weight per volume of solution), layering the solution on the surface of the contained control and allowing the solution to cool until it forms a mechanically stable, thin but nonporous, plural phase gel seal at the surface of the control which is impregnated with said chemicals, is compatible with blood, is nonporous to the blood gases in the control and prevents changes in equilibrium between the liquid and gaseous phases in the blood gas control in the container.
Dependencies are inferred from the claim text.