US 4,396,510 AGranted

Mass transfer device

AssigneeBio-Med Corporation

InventorPaul Hsei

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Abstract

A separatory apparatus for selectively separating components of multi-component fluids in which a multiplicity of contiguous capillary fibers are uniquely arranged and supported within a housing having a non-cylindrically shaped central portion. In the primary application of the device a multicomponent fluid such as blood flows interiorly of the fibers and a dialysate flows externally of the fibers. Embodied proximate the fluid inlet portion of the device is a uniquely configured fluid distribution element which stratigically positions the fibers and directs the flow of the external fluid, or dialysate, uniformly through the passageways defined by the external walls of the fibers. In this way channeling of the fluid is eliminated and a uniform fluid flow along the external surfaces of each fiber is realized. In this way all of the fibers can be effectively used for mass transfer thereby markedly improving the overall efficiency of the device.

Claims4

Dependent claims

A dialyzer comprising:

(a) a housing including an oval shaped central hollow body portion and integral first and second enlarged end portions which are circular in cross-section at any point, said first end portion having a first fluid inlet for passage of a dialysate fluid and said second portion having a first fluid outlet for passage of the modified dialysate fluid;
(b) a plurality of fiber bundles housed within and supported by said central hollow body portion, said fiber bundle comprising a multiplicity of longitudinally extending, contiguous capillary fibers each having an interior bore throughout its length and each having open first and second end portions extending respectively into said first and second end portions of said housing, said fibers being arranged within each said bundle to provide a multiplicity of substantially uniform fluid flow passageways interiorly of said fibers and exteriorly between said contiguous fibers;
(c) first and second closure means adapted to cover respectively said first and second end portions of said housing, said first closure means having a second fluid inlet in communication with said first end portions of said hollow fibers for passage of blood and said second closure means having a second fluid outlet in communication with said second end portions of said hollow fibers for passage of the treated blood;
(d) sealing means disposed within said first end portion of said housing for preventing flow of the dialysate fluid between said first fluid inlet and the interior bores of said hollow fibers, said sealing means being configured and arranged to cause said dialysate fluid to flow uniformly through said fluid flow passageways between contiguous hollow fibers;
(e) sealing means disposed within said second end portion of said housing for preventing flow of treated blood between said interior bores of said hollow fibers and said first fluid outlet;
and
(f) means disposed intermediate said first end portion of said housing for directing the flow of said dialsyate fluid from said first fluid inlet into the passageways formed between said contiguous hollow fibers of said fiber bundle whereby said dialysate fluid will flow uniformly between said fibers, said means comprising a comb shaped element having a plurality of fingers extending transversely of said first end portion.

4 more elements

A separatory apparatus for selectively separating components of multi-component fluids, comprising:

(a) an elongated housing including a non-cylindrically shaped central hollow body portion and integral first and second enlarged end portions which are circular in cross-section at any point, said first end portion having a first fluid inlet for passage of a first fluid and said second portion having a first fluid outlet for passage of a second fluid;
(b) at least one fiber bundle housed within and supported by said central hollow body portion, said fiber bundle comprising a multiplicity of longitudinally extending, contiguous, hollow capillary fibers each having an interior bore throughout its length and each having open first and second end portions extending respectively into said first and second end portions of said housing, said fibers being arranged within each said bundle to provide a multiplicity of substantially uniform fluid flow passageways interiorly of said fibers and exteriorly between said contiguous fibers;
(c) first and second cover means adapted to cover respectively said first and second end portions of said housing, said first cover means having a second fluid inlet in communication with said first end portions of said hollow fibers for passage of a third fluid and said second cover means having a second fluid outlet in communication with said second end portions of said hollow fibers for passage of a fourth fluid;
(d) sealing means disposed within said first end portion of said housing for preventing fluid flow between said first fluid inlet and the interior bores of said hollow fibers, said sealing means being configured and arranged to cause said first fluid to flow uniformly through said fluid flow passageways between contiguous hollow fibers;
(e) sealing means disposed within said second end portion of said housing for preventing fluid flow between said interior bores of said hollow fibers and said first fluid outlet;
and
(f) distributor means disposed intermediate said first end portion of said housing for directing the flow of said first fluid from said first fluid inlet into the passageways formed between said contiguous hollow fibers of said fiber bundle whereby said first fluid will flow uniformly between said fibers, said distributor means comprising a shaped element adapted to engage a portion of said fibers of said fiber bundle to cause the first end portions thereof to diverge radially outwardly within said first end portion, said shaped element comprising a combed shaped element having a plurality of substantially vertically extending fingers.

4 more elements

A separatory apparatus for selectively separating components of multi-component fluids, comprising:

(a) an elongated housing including a non-cylindrically shaped central hollow body portion and integral first and second enlarged end portions which are circular in cross-section at any point, said first end portion having a first fluid inlet for passage of a first fluid and said second portion having a first fluid outlet for passage of a second fluid;
(b) a plurality of fiber bundles housed within and supported by said central hollow body portion, said fiber bundle comprising a multiplicity of longitudinally extending, contiguous, hollow capillary fibers each having an interior bore throughout its length and each having open first and second end portions extending respectively into said first and second end portions of said housing, said fibers being arranged within each said bundle to provide a multiplicity of substantially uniform fluid flow passageways interiorly of said fibers and exteriorly between said contiguous fibers;
(c) first and second cover means adapted to cover respectively said first and second end portions of said housing, said first cover means having a second fluid inlet in communication with said first end portions of said hollow fibers for passage of a third fluid and said second cover means having a second fluid outlet in communication with said second end portions of said hollow fibers for passage of a fourth fluid;
(d) sealing means disposed within said first end portion of said housing for preventing fluid flow between said first fluid inlet and the interior bores of said hollow fibers, said sealing means being configured and arranged to cause said first fluid to flow uniformly through said fluid flow passageways between contiguous hollow fibers;
(e) sealing means disposed within said second end portion of said housing for preventing fluid flow between said interior bores of said hollow fibers and said first fluid outlet;
and
(f) distributor means disposed intermediate said first end portion of said housing for directing the flow of said first fluid from said first fluid inlet into the passageways formed between said contiguous hollow fibers of said fiber bundle whereby said first fluid will flow uniformly between said fibers, said distributor means comprising a shaped element adapted to engage a portion of said fibers of said fiber bundle to cause the first end portions thereof to diverge radially outwardly within said first end portion, said shaped element comprising a lattice of rows and columns defining a plurality of openings each of which is adapted to support a fiber bundle proximate the end portions thereof.

4 more elements

Dependencies are inferred from the claim text.