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AssigneeByk Gulden Lomberg Chemische Fabrik GmbH
InventorsKlaus Eistetter, Erich Rapp, Horst Wolf
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Quinolinone-alkanecarboxylic acids of the formula I ##STR1## wherein R.sup.1, R.sup.2 and R.sup.3 are identical or different and denote hydrogen atom, a halogen atom, a hydroxyl group, an alkoxy group with 1 to 4 carbon atoms, an amino group, a dialkylamino group, the alkyl radicals having 1 to 4 carbon atoms, or a nitro group, R.sup.4 and R.sup.5 are identical or different and denote a hydrogen atom, a halogen atom, an alkoxy group with 1 to 4 carbon atoms, a hydroxyl group, an amino group or a dialkylamino group, the alkyl radicals having 1 to 4 carbon atoms, or R.sup.4 and R.sup.5 together denote a methylenedioxy group bonded to two adjacent ring carbon atoms, and A denotes an alkylene group with 1 to 5 carbon atoms, and esters thereof with alkanols with 1 to 5 carbon atoms, and salts thereof with inorganic and organic bases are new compounds. They display a hyperglycaemic action in warm-blooded animals. Processes for the preparation of the new compounds are given.
A substituted quinolinone of the general formula I ##STR13## wherein R.sup.1, R.sup.2 and R.sup.3 are identical or different and each denotes a hydrogen atom, a halogen atom, a hydroxyl group, an alkoxy group with 1 to 4 carbon atoms, an amino group, a dialkylamino group, each alkyl radical having 1 to 4 carbon atoms, or a nitro group,
A substituted quinolinone of the general formula I* ##STR14## wherein R.sup.1*, R.sup.2* and R.sup.3* are identical or different and each denotes a hydrogen atom, a halogen atom, an alkoxy group with 1 to 4 carbon atoms or a hydroxyl group,
A substituted quinolinone of the general formula I** ##STR15## wherein R.sup.1*** and R.sup.2** denote a hydrogen atom,
7-Chloro-1,2-dihydro-2-oxo-3-phenyl-quinol-1-yl-acetic acid or a salt thereof with inorganic and organic base.
Dependencies are inferred from the claim text.