Back to results
US 4,395,408 AGranted
Steroids
AssigneeRoussel Uclaf
InventorsVesperto Torelli, Roger Deraedt, Lucien Nedelec
Life of this patent
Estimating the term…
Loading patent…
Loading patent…
AssigneeRoussel Uclaf
InventorsVesperto Torelli, Roger Deraedt, Lucien Nedelec
Estimating the term…
Novel 3-amino-steroids of the formula ##STR1## wherein R.sub.1 is selected from the group consisting of hydrogen and methyl, W is selected from the group consisting of hydrogen and --OH and taken together with x forms ethylidene, X is selected from the group consisting of ethyl, ##STR2## and taken together with W forms ethylidene and the wavy lines signify that the substituents are in the .alpha. or .beta.-position with the proviso that when R.sub.1 is methyl and X is ethyl, ##STR3## W is --OH and their non-toxic, pharmaceutically acceptable acid addition salts and their preparation and intermediates therefore capable of stimulating immunitary activity.
A compound selected from the group consisting of (Z) 3.alpha.-amino-.DELTA..sup.17(20) -5.alpha.-pregnene, (20S) 3.alpha.-amino-19-nor-5.alpha.-pregnane-20-ol and (20S) 3.beta.-amino-19-nor-5.alpha.-pregnane-20-ol and their non-toxic, pharmaceutically acceptable acid addition salts.
A compound of claim 19 selected from the group consisting of (Z) 3.alpha.-amino-.DELTA..sup.17(20) -5.alpha.-pregnene and its non-toxic, pharmaceutically acceptable acid addition salts.
A compound having the formula of ##STR25## wherein R.sub.1 is selected from the group consisting of hydrogen and methyl and the wavy line indicates the .alpha.- or .beta.-position.
Dependencies are inferred from the claim text.