Unsymmetrically substituted dicarboxylic-acid-bis-(2,4,6-triiodo-anilides), their preparation, and x-ray contrast media containing same

Abstract

Unsymmetrically substituted dicarboxylic-acid-bis-(2,4,6-triiodo-anilides) of formula I ##STR1## wherein X is straight-chain or branched alkylene interrupted by one or more oxygen atoms, R.sup.1 is --NHacyl, --CH.sub.2 NHacyl, or --CONHR.sup.3 wherein R.sup.3 is hydrogen or a lower straight-chain or branched optionally mono- or poly-hydroxylated, alkyl residue, and where any hydroxyl groups present may be functionally modified, and R.sup.2 is hydrogen or lower alkyl, and their salts, are extraordinarily well suited, in view of their good pharmacological and physico-chemical properties, as water-soluble x-ray contrast media for all fields of application, in particular for i.v. cholegraphy and for computer tomography.

Dependencies are inferred from the claim text.