2-[(Phenylthio)methyl or ethyl]pyridine derivatives
AssigneeJohn Wyeth & Brother Limited
InventorRoger Crossley
Life of this patent
Estimating the term…
Abstract
The invention provides a compound of formula I ##STR1## wherein R represents hydrogen, lower alkyl, phenyl, halophenyl, loweralkylphenyl, loweralkoxyphenyl or aralkyl of 7 to 12 carbon atoms, R.sup.1 represents hydrogen or fluorine, R.sup.2 represents hydrogen, fluorine, chlorine or trifluoromethyl, n is 1 or 2 or pharmaceutically acceptable acid addition salt thereof. Pharmaceutical compositions containing the compounds are also covered as are methods of treating ulcers or hypersecretion using the compounds. Corresponding thiocompounds, useful as intermediates, are also disclosed.
Claims6
A compound of formula II:
- ##STR7## wherein R represents hydrogen or lower alkyl, R.sup.1 represents hydrogen or fluorine, R.sup.2 represents hydrogen, fluorine or chlorine, n is 1 or 2 and at least one of R, R.sup.1 and R.sup.2 is other than hydrogen, and the pharmaceutically acceptable salts thereof.
Dependencies are inferred from the claim text.