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US 4,394,504 AGranted
Cephalosporin derivatives
AssigneeAmerican Home Products Corporation
InventorsThomas J. Commons, John R. Potoski
Life of this patent
Estimating the term…
Abstract
7-[2-(3-Amino-5-isoxazolyl)-2-alkyloxy-iminoacetamido]-ceph-3-em-4-carboxyl ic acid derivatives are antibacterial agents effective against gram-positive and gram-negative bacterium.
Claims3
A compound of the formula:
- ##STR6## in which:
- R.sup.1 is H, alkyl of 1 to 4 carbon atoms, alkenyl of 2 to 4 carbon atoms, alkynyl of 2 to 4 carbon atoms, arylalkyl of 7 to 10 carbon atoms, 2-carboxyprop-2-yl, carboxymethyl, alkanoyl of 2 to 4 carbon atoms or .alpha.-phenylalkanoyl of 8 to 10 carbon atoms;
- R.sup.2 is H, hydroxy, alkanoyloxy of 2 to 6 carbon atoms, carbamoyloxy, ##STR7## where R.sup.4 is hydrogen or alkyl of 1 to 4 carbon atoms or ##STR8## where R.sup.5 is hydrogen or alkyl of 1 to 4 carbon atoms, vinyl, sulfonyloxymethyl or carboxymethyl;
- or a pharmaceutically acceptable salt thereof.
1 more element
Dependencies are inferred from the claim text.