Production of 2-benzazepines
AssigneeHoffmann-La Roche Inc.
InventorEugene J. Trybulski
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Abstract
Compounds of the formula ##STR1## wherein X and Y are selected from the group consisting of hydrogen, halogen and trifluoromethyl, are disclosed. The compounds are useful as intermediates in the production of 2-benzazepines, compounds of pharmacological activity. Also disclosed are other intermediates and processes for their production.
Claims1
A process to produce a compound of the formula ##STR6## wherein X and Y are selected from the group consisting of hydrogen, halogen and trifluoromethyl, which consists essentially of the reaction of a compound of the formula ##STR7## wherein X and Y are as above, with a mixture of a catalytic amount of mercuric sulfate and an excess of a C.sub.1 to C.sub.4 carboxylic acid in an inert solvent at from about -10.degree. C. to room temperature.
Dependencies are inferred from the claim text.