Method for producing L-glutamic acid by fermentation
AssigneeAjinomoto Co., Inc.
InventorsTakayasu Tsuchida, Shigeru Nakamori
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Abstract
An L-glutamic acid producing microorganism, which is obtained by incorporation into a host strain of the genus Escherichia of a hybrid plasmid having inserted therein a DNA fragment with genetic information controlling L-glutamic acid production, said fragment being derived from a donor strain of Escherichia which is capable of producing L-glutamic acid useful for the production of high levels of L-glutamic acid.
Claims16
A method of producing L-glutamic acid by fermentation which comprises culturing in a culture medium an L-glutamic acid producing microorganism which is obtained by incorporating a hybrid plasmid having inserted therein a DNA fragment with genetic information controlling L-glutamic acid production, said fragment being derived from a donor strain of the genus Escherichia which is capable of producing L-glutamic acid, into a recipient strain of the genus Escherichia, wherein said L-glutamic acid producing microorganism is the transformant NRRL B-12286, NRRL B-12299, NRRL B-12300, NRRL B-12301, or NRRL B-12302.
An L-glutamic acid producing transformant of the genus Escherichia containing a hybrid plasmid having inserted therein a DNA fragment with genetic information controlling L-glutamic acid production derived from a donor mutant of the genus Escherichia capable of producing L-glutamic acid, said mutant being resistant to lysine analog, wherein said transformant is NRRL B-12286, NRRL B-12299, NRRL B-12300, NRRL B-12301, or NRRL B-12302.
Dependencies are inferred from the claim text.