US 4,393,010 AGranted

Nucleosidic phosphorylating agent and methods

AssigneeGenentech, Inc.

InventorRoberto Crea

Life of this patent

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Abstract

Compounds of the formula ##STR1## where R is a base labile substituted-phenyloxy protecting group, are useful as phosphorylating reagents in the synthesis of oligonucleotides by a phosphotriester method.

Claims3

Dependent claims

A compound of structure ##STR8## where R is a base labile phenyloxy protecting group.

Dependencies are inferred from the claim text.

Facts

Application: 06/294,689Filed 20 Aug 1981 · division
Priority: 26 Dec 1979
Granted: 12 Jul 1983
Term ends: Not estimatedThe source records don’t support an estimate.

Classification6 codes

C07H 21/00
Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate
C07F 9/1406
Containing P-halide groups: containing the structure Hal-P-O-aryl
Y02P 20/55
Improvements relating to the production of bulk chemicals: design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
C07H
Sugars

Family

Serial107,055Parent of this division · filed 26 Dec 1979
US 4,310,662 AParent of this division
US 4,393,010 AThis patent

From the US filing history. Foreign family members aren’t listed.

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