7-Substituted benzopyranes and process for the preparation thereof

A compound of the formula (Ia) ##STR20## or a pharmaceutically acceptable acid addition or quaternary C.sub.1 -C.sub.4 -alkyl ammonium halide, sulfate or phosphate salt thereof, wherein

• R.sub.1 and R.sub.2 are each hydrogen, C.sub.1 to C.sub.6 alkyl, hydroxy-alkyl, alkenyl, cycloalkyl, phenylalkyl, or dimethoxyphenyl-alkyl.

A compound of the formula (Ib) ##STR21## or a pharmaceutically acceptable acid addition or quaternary C.sub.1 -C.sub.4 -alkyl ammonium halide, sulfate or phosphate salt thereof, wherein

• R.sub.1 and R.sub.2 are each hydrogen, C.sub.1 to C.sub.6 alkyl, hydroxy-alkyl, alkenyl, cycloalkyl, phenyl-alkyl, or dimethoxy-phenyl-alkyl.

A compound of the formula (Ic) ##STR22## or a pharmaceutically acceptable acid addition or quaternary C.sub.1 -C.sub.4 -alkyl ammonium halide, sulfate or phosphate salt thereof, wherein

• R.sub.1 and R.sub.2 are each hydrogen, C.sub.1 to C.sub.6 alkyl, hydroxy-alkyl, alkenyl, cycloalkyl, phenyl-alkyl, or dimethoxy-phenylalkyl;
• and
• n is 1 or 2.

A compound of the formula (Id) ##STR23## or a pharmaceutically acceptable acid addition or quaternary C.sub.1 -C.sub.4 -alkyl ammonium halide, sulfate or phosphate salt thereof where

• R.sub.1 and R.sub.2 are each hydrogen, C.sub.1 to C.sub.6 alkyl, hydroxy-alkyl, alkenyl, cycloalkyl, phenyl-alkyl, or dimethoxy-phenylalkyl;
• R.sub.3 is C.sub.1 to C.sub.4 alkyl or phenyl;
• and n is 1 or 2.

A compound of the formula (Ie) ##STR24## or a pharmaceutically acceptable acid addition or quaternary C.sub.1 -C.sub.4 -alkyl ammonium halide, sulfate or phosphate salt thereof, wherein

• R.sub.1 and R.sub.2 are each hydrogen, C.sub.1 to C.sub.6 alkyl, hydroxy-alkyl, alkenyl, cycloalkyl, phenyl-alkyl, or dimethoxy-phenylalkyl;
• and
• R.sub.3 is hydrogen or C.sub.1 to C.sub.4 alkyl.

A compound of the formula ##STR25## or a pharmaceutically acceptable acid addition or quaternary C.sub.1 -C.sub.4 -alkyl ammonium halide, sulfate or phosphate salt thereof, wherein

• R.sub.1 and R.sub.2 are each hydrogen, C.sub.1 to C.sub.6 alkyl, hydroxyalkyl, alkenyl, cycloalkyl, phenyl-alkyl or dimethoxy-phenyl-alkyl.

4-cyclohexylamino-1-(2-phenyl-3,4-dihydro-2H-1-benzopyrane-7-yloxy)-2-buta nol or a pharmaceutically effective salt thereof.