Plasma protein fraction substantially free of acetate ions
AssigneeCutter Laboratories, Inc.
InventorsPaul K. Ng, Michael A. Fournel
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Abstract
Stable plasma protein fractions (PPF) substantially free of vasodepressant amounts of acetate ions are disclosed. Solutions of the disclosed PPF are suitable for intravenous administration to patients without deleterious vasodepressor effects. Methods are also described for preparing the aforementioned PPF.
Claims17
A stable human plasma protein fraction precipitated from Supernatant IV-1 of the Cohn fractionation scheme as described in U.S. Pat. No. 2,958,628 wherein the plasma protein fraction consists essentially of at least eighty three percent albumin and no more than seventeen percent alpha and beta globulin and wherein the acetate ion concentration is about that ordinarily found in human blood plasma.
A stable human plasma protein fraction precipitated from Supernatant IV-1 of the Cohn fractionation scheme as described in U.S. Pat. No. 2,958,628 wherein the plasma protein fraction consists essentially of at least eighty three percent albumin and no more than seventeen percent alpha and beta globulin and wherein the acetate ion concentration is about 0.2-0.65 milliequivalents per liter.
Dependencies are inferred from the claim text.