Coated sutures
AssigneeEthicon, Inc.
InventorFrank V. Mattei
Life of this patent
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Abstract
A coated, absorbable suture wherein a particular absorbable composition comprising a film-forming polymer, a lubricant and a hydrophobic material is provided for coating sutures, particularly multifilament synthetic absorbable sutures, in order to improve the smoothness in tie-down properties of the sutures.
Claims17
A finished multifilament absorbable surgical suture having improved tie down properties characterized in that the surface of the suture is coated with an absorbable composition providing in combination:
- a. from about 10 to 50 percent by weight of an absorbable film forming polymer selected from the group consisting of homopolymers and copolymers of lactide and glycolide, copolymers of vinyl acetate with unsaturated carboxylic acids, water soluble or dispersible cellulose derivatives, natural gums, high molecular weight crystalline ethylene oxide polymers, polyacrylamide, polyvinyl alcohol, polyvinyl pyrrolidone, gelatin, collagen, polyamino acids, and conjugated unsaturated triglycerides,
- b. from about 20 to 60 percent by weight of an absorbable lubricant comprising a polyalkylene glycol having a molecular weight between about 5,000 and 200,000, and
- c. from about 10 to 40 percent by weight of an absorbable hydrophobic material selected from the group consisting of higher fatty acids and esters of higher fatty acids.
A method for improving the tie down characteristics of an absorbable multifilament suture which comprises coating said suture with an absorbable composition providing in combination:
- a. from about 10 to 50 percent by weight of an absorbable film forming polymer selected from the group consisting of homopolymers and copolymers of lactide and glycolide, copolymers of vinly acetate with unsaturated carboxylic acids, water soluble or dispersible cellulose derivatives, natural gums, high molecular weight crystalline ethyleneoxide polymers, polyacrylamide, polyvinyl alcohol, polyvinyl pyrrolidone, gelatin. collagen, polyamino acids, and conjugated unsaturated triglycerides,
- b. from about 20 to 60 percent by weight of an absorbable lubricant comprising a polyalkylene glycol having a molecular weight between about 5,000 and 200,000 and
- c. from about 10 to 40 percent by weight of an absorbable hydrophobic material selected from the group consisting of higher fatty acids and esters of higher fatty acids.
A method for improving the tie-down characteristics of a multifilament suture composed of an absorbable synthetic polymer selected from the group consisting of homopolymers and copolymers of lactide and glycolide which comprises coating said suture with an absorbable coating composition comprising (1) from about 10 to bout 50 weight percent of a copolymer of lactide and glycolide, (2) from about 20 to about 60 weight percent of a polyethylene glycol having a molecular weight between about 5,000 and about 50,000 and (3) from about 10 to about 40 weight percent of hydrogenated castor oil.
Dependencies are inferred from the claim text.