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US 2026/0308184 A1Published application
Substituted pyrimidinedione compounds, compositions, and uses thereof
AssigneeLakewood Amedex, Inc.
InventorsKelvin Cooper, Steven Kates
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Abstract
Substituted pyrimidinedione compounds of Formula (I) and methods of use are disclosed.
Claims47
A compound having the formula:
- or a pharmaceutically acceptable salt thereof, wherein
- R1 is (C1-C8)straight-chain alkyl, (C3-C8)branched-chain alkyl, (C3-C8)cycloalkyl, phenylalkyl, alkylcycloalkyl, hydroxy(C1-C8)straight-chain alkyl, hydroxy(C3-C8)branched-chain alkyl, alkoxy(C1-C8)straight-chain alkyl, alkoxy(C3-C8)branched-chain alkyl, halo(C1-C8)straight-chain alkyl, or halo(C3-C8)branched-chain alkyl;
- R2, R3, and R4 are each independently H, OH, oxy(C1-C8)straight-chain alkyl, oxy(C1-C8)branched-chain alkyl, CF3, or F;
- and
- R5 and R6 are each independently H, F, Cl, CF3, CH3, or are bound to one another through a C—C bond to form a C3-C8 cycloalkyl.
2 more elements
A compound having the formula selected from the group consisting of Formula (II) to Formula (IX):
- and a pharmaceutically acceptable salt thereof.
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Dependencies are inferred from the claim text.