US 2026/0308171 A1Published application

Heterobifunctional compounds and methods of treating disease

AssigneeHalda Therapeutics OpCo, Inc.

InventorsKyle J. Eastman, Katherine J. Kayser-Bricker, James John Mousseau, Kanak Shail Raina, Lei Zhou, Gengjie Lin, Zhixiong Liao, Xiaofeng Wu, Xing Qu, Ming Gao, Lele Sun, Yurong Zhang

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Abstract

The invention provides heterobifunctional compounds, pharmaceutical compositions, and their use treating disease, such as cancer.

Claims25

Dependent claims

A crystalline compound of Formula II-5:

Dependencies are inferred from the claim text.

Facts

Application: 19/686,162Filed 22 May 2026
Priority: CN 202411404732.79 Oct 2024
Published: 8 Oct 2026
Term ends: Not estimatedThe source records don’t support an estimate.

Classification7 codes

C07D 495/14
In which the condensed system contains three hetero rings: ortho-condensed systems
A61K 31/551
Having seven-membered rings, e.g. azelastine, pentylenetetrazole: having two nitrogen atoms, e.g. dilazep
A61P 35/00
Antineoplastic agents
C07D 519/00
Heterocyclic compounds containing more than one system of two or more relevant

Family

Application63/544,710Us provisional application · filed 18 Oct 2023
Application63/618,075Us provisional application · filed 5 Jan 2024
Application63/563,000Us provisional application · filed 8 Mar 2024
Application18/920,528Continuation · filed 18 Oct 2024
Application19/686,162Continuation
US 12,668,599 B2Related patent
US 2025/0136611 A1Published application
US 2026/0308171 A1This patent

From the US filing history. Foreign family members aren’t listed.

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