Filling Process for Pharmaceutical Compositions
AssigneeAmgen Inc.
InventorsRichard Crowther, Julian Jazayeri, Seyed Reza Mirhassani Moghaddam, William Vega Vega
Life of this patent
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AssigneeAmgen Inc.
InventorsRichard Crowther, Julian Jazayeri, Seyed Reza Mirhassani Moghaddam, William Vega Vega
Estimating the term…
A method for reducing material usage in vessels is provided. The method includes obtaining historical fill weight data indicating actual, per-unit fill weight volumes for a plurality of vessels. The method also includes generating, based on analysis of the historical fill weight data, a distribution of simulated fill weights. The method further includes randomly sampling the distribution of simulated fill weights to select a subset of the simulated fill weights, and performing a quality check on the subset of the simulated fill weights. The method yet further includes generating a modified distribution of simulated fill weights at least by removing, from the distribution of simulated fill weights, samples of the subset that failed the quality check. The method also includes converting the modified distribution of simulated fill weights to a distribution of fill volumes, and calculating a distribution of deliverable volumes based on the distribution of fill volumes.
A method of filling a drug product in vessels, the method comprising:
A non-transitory computer-readable medium having computer-readable instructions stored thereon that, when executed by one or more processors, cause the one or more processors to:
Dependencies are inferred from the claim text.