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US 2026/0306710 A1Published application
Photocurable hydrogel compositions
AssigneeTympanogen, Inc.
InventorsElaine HORN-RANNEY, Sithara NAIR, Bethany young
Life of this patent
Estimating the term…
Abstract
The present disclosure provides photocurable hydrogel compositions and methods of using in the treatment of tympanic membrane perforations.
Claims58
A pre-lyophilized composition comprising:
- (i) a base comprising about 40 wt % to about 80 wt % methacrylated chitosan, about 20 wt % to about 40 wt % hyaluronic acid and about 0.01 wt % to about 0.5 wt % photoinitiator, 0 wt % to about 20 wt % arginine;
- and
- (ii) a diluent.
A lyophilized composition, comprising:
- about 0 wt % to about 10 wt % water,
- about 40 wt % to about 80 wt % methacrylated chitosan,
- about 20 wt % to about 40 wt % hyaluronic acid,
- about 0.01 wt % to about 0.5 wt % of a photoinitiator, and
- about 0 wt % to about 20 wt % arginine.
2 more elements
A semi-gel composition comprising:
- about 80 wt % to about 99 wt % of a diluent,
- about 1 wt % to about 3 wt % methacrylated chitosan,
- about 0.5 wt % to about 2 wt % hyaluronic acid,
- about 0.0010 wt % to about 0.01 wt % of a photoinitiator,
- and about 0 wt % to about 0.5 wt % arginine.
2 more elements
A cured composition comprising:
- about 80 wt % to about 99 wt % of a diluent;
- about 1 wt % to about 3 wt % methacrylated chitosan,
- about 0.5 wt % to about 2 wt % hyaluronic acid,
- about 0.0010 wt % to about 0.01 wt % of a photoinitiator;
- and
- about 0 wt % to about 0.5 wt % arginine.
3 more elements
Dependencies are inferred from the claim text.