Quantitative Analysis of Polysorbate Oxidation
OwnerHui XIAO, Sisi ZHANGinventors
Life of this patent
Estimating the term…
Abstract
Methods for assessing oxidation of a polysorbate in a formulation can include determining a concentration of one or more oxidation markers of the polysorbate in a formulation that at least initially included the polysorbate. The one or more oxidation markers can include or can be a compound having carboxylic acid and/or an aldehyde.
Claims20
A method for assessing oxidation of a polysorbate in a formulation, comprising determining a concentration of one or more oxidation markers of the polysorbate in a formulation that at least initially included the polysorbate, wherein the one or more oxidation markers comprise a carboxylic acid and/or an aldehyde.
A method for assessing oxidation of polysorbate 80 (PS80) in a formulation, comprising determining a concentration of octanoic acid in the formulation at a first time point.
Dependencies are inferred from the claim text.