A 1,5-dihydro-4h-pyrrolo[3,2-c] pyridin-4-one for use in the treatment of cancer

Abstract

The present application discloses a chemical entity of formula (I) (or a pharmaceutically acceptable salt and/or hydrate and/or cocrystal and/or drug combination thereof) that inhibits epidermal growth factor receptor (EGFR, ERBB1) and/or Human epidermal growth factor receptor 2 (HER2, ERBB2). The compound of formula (I) is useful, e.g., for treating a condition, disease or disorder in which increased (e.g., excessive) EGFR and/or HER2 activation contributes to the pathology and/or symptoms and/or progression of the condition, disease or disorder (e.g., cancer) in a subject (e.g., a human). This application also provides compositions containing the same as well as methods of using and making the same.

Dependencies are inferred from the claim text.