Substituted bicyclic heterocycle compounds, compositions, and uses thereof

A compound having the formula:

• or a pharmaceutically acceptable salt thereof, wherein
• R1 is (C1-C8)straight-chain alkyl, (C3-C8)branched-chain alkyl, (C3-C8)cycloalkyl, phenylalkyl, alkylcycloalkyl, hydroxy(C1-C8)straight-chain alkyl, hydroxy(C3-C8)branched-chain alkyl, alkoxy(C1-C8)straight-chain alkyl, alkoxy(C3-C8)branched-chain alkyl, halo(C1-C8)straight-chain alkyl, or halo(C3-C8)branched-chain alkyl;
• R2, R3, and R4 are each independently H, OH, oxy(C1-C8)straight-chain alkyl, oxy(C1-C8)branched-chain alkyl, CF3, or F;
• Heterobicycle is selected from the group consisting of
• R5 is H, (C1-C5)straight-chain alkyl, (C1-C5)branched-chain alkyl, or CF3;
• R6 and R7 are each independently selected from H, N(R8)R9, (C1-C5)straight-chain alkyl, (C1-C5)branched-chain alkyl, or CF3;
• and
• R8 and R9 are each independently selected from H, (C1-C5)straight-chain alkyl, (C1-C5)branched-chain alkyl, or are bound to one another through a C—C bond to form a C3-C8 cycloalkyl.