Compositions and methods of controlling mammalian satiety

A particle that is blend-able within a dairy product, the particle comprising a composition comprising:

• eicosapentaenoic acid in a range from about 25% (w/w) to about 50% (w/w);
• and
• α-tocopherol in a range from about 3% (w/w) to about 10% (w/w),
• wherein the particle comprises a mean diameter (Dv50) of from about 300 μm to about 900 μm.

A coating method comprising:

• solubilizing a first amount of encapsulant via at least one of melting and solvent-solubilization;
• adding a second amount of nutrient payload to a coater, the coater comprising at least one of a pan coater, a fluidized bed coater and another coater;
• applying at least one of fluidization, mixing, and rotation to the nutrient payload in the coater;
• administering the melted or solubilized encapsulant to the mixed, rotated and/or fluidized payload via at least one of spraying, coating, and atomization thereby forming coated particles;
• and
• adding at least one of anti-caking and flow-aid agents before, during and/or after the administering process.

A dissolution method comprising:

• adding a satiety modulating composition to dissolution media;
• initiating a dissolution assay comprising one or more desired conditions, the one or more desired conditions comprising at least one of a mixing condition, a specific temperature range, and specific pH range;
• and
• collecting at least a portion of the dissolution media at various time points.