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OwnerAnita Shukla, Camila Carvalho +1inventors
InventorsAnita Shukla, Camila Carvalho, Veronica LaMastro
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The present disclosure provides a liposome composition comprising a plurality of liposomes, wherein each liposome of the plurality of liposomes comprises a lipid bilayer comprising hydrogenated soy phosphatidylcholine (HSPC), cholesterol (CHOL), and farnesol (FAR). Each liposome may be coated on the outer lipid bilayer with a negatively charged polymer such as poly(acrylic acid) (PAA), heparin, or other polyanions. Each liposome may further encapsulate one or more antifungal therapeutics. Methods of treating or preventing fungal infections, including vulvovaginal candidiasis caused by C. albicans, using the liposome composition are also provided. Methods of making the liposome formulation are further provided.
A liposome composition comprising a plurality of liposomes wherein each liposome of the plurality of liposomes comprises a lipid bilayer comprising hydrogenated soy phosphatidylcholine (HSPC), cholesterol (CHOL), and/or farnesol (FAR).
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A method of making a liposome formulation, comprising
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Dependencies are inferred from the claim text.