A Non-Adherent Absorbent Article
AssigneeSerigen Mediproducts Pvt. Ltd.
InventorsRaeesa SAYYAD, Lakshmi Raghavan PILLAI, Nimisha PAREKH, Swati Govind SHUKLA, Anuya NISAL, Rucha DESHPANDE
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Abstract
The present invention relates to a non-adherent, absorbent article with an optimum moisture vapor transmission rate (MVTR) that may be used as wound dressing or as an anti-adhesive membrane in surgical devices. The present invention further relates to an article comprising of a polymer deposited/coated on to a woven and/or non-woven mesh and to the process of fabrication thereof.
Claims25
A non-adherent, absorbent article with optimum moisture vapor transmission rate (MVTR) comprising;
- i. a first contact layer of regenerated silk fibroin (SF) containing a hydrophilic natural polymer and/or a hydrophilic synthetic polymer or a combination thereof coated/deposited on to a mesh;
- and
- ii. optionally loaded with a bioactive molecules,
- wherein the SF to the hydrophilic natural polymer and/or the hydrophilic synthetic polymer or a combination thereof are in the ratio ranging between 95:05 to 50:50.
A process for fabricating non-adherent, absorbent article with optimum MVTR comprising;
- i. preparing the regenerated silk fibroin solution;
- ii. mixing the regenerated SF solution with the hydrophilic synthetic polymer and/or the hydrophilic natural polymer or a combination thereof in a weight ratio ranging between 95:05 to 50:50 to obtain a polymer solution;
- iii. placing the mesh into a mold;
- iv. pouring a required amount of the polymer solution of step (ii) in to the mold and freezing, followed by lyophilization;
- v. annealing the lyophilized product with lower alcohol.
A non-adherent, absorbent wound dressing composition with optimum moisture vapor transmission rate (MVTR) comprising;
- i. a regenerated SF along with a hydrophilic synthetic polymer and/or a hydrophilic natural polymer or a combination thereof coated/deposited on to a mesh;
- and
- ii. optionally loaded with a bioactive molecule in an amount of 0.01 to 5 mg/ml;
- wherein the SF to the hydrophilic synthetic polymer and/or a hydrophilic natural polymer or a combination thereof is in a weight ratio ranging between 95:05 to 50:50.
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Dependencies are inferred from the claim text.