Flow restriction devices with covered portions

An implantable device for dynamically occluding a blood vessel, the implantable device comprising:

• an annular frame having a lumen extended therethrough;
• a sealing element disposed along an exterior of the frame and along an interior of the frame opposite the exterior of the frame, the sealing element being configured to seal portions of the frame between the exterior and the interior of the frame;
• and
• an actuation member coupled to the frame and configured to alter a diameter of the frame to modulate blood flow through the lumen.

A method of treatment for reducing blood flow at a target site in a blood vessel of a subject, the method comprising:

• implanting a device in the blood vessel, the device comprising:
• a frame having an inflow end, an actuatable outflow end, and a longitudinal axis extending therethrough;
• a first polymeric covering disposed on an inner surface of the frame;
• second polymeric disposed on an outer surface of the frame, wherein the first polymeric covering is coupled to portions of the second polymeric covering to form a circumferentially sealed space defined to extend around a portion of a circumference of the outer surface of the frame;
• and
• a skirt membrane wrapped around an exterior surface of the second polymeric covering;
• and
• actuating the outflow end of the device to modulate a flow of blood within the blood vessel.