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US 2026/0265312 A1Published application
Vaccines targeting pseudomonas aeruginosa
AssigneeEvaxion Biotech A/S
InventorsNiels Iversen Møller, Andreas Holm Mattsson
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Abstract
Immunogenic proteins from Pseudomonas aeruginosa as well as nucleic acids, vectors and transformed cells useful for expression of the proteins. Also disclosed are methods for prophylaxis of infection with Pseudomonas aeruginosa using the proteins, nucleic acids, vectors or transformed cell.
Claims30
A pharmaceutical composition comprising an immunological adjuvant and a polypeptide, said polypeptide comprises:
- a) amino acid sequence SEQ ID NO:
- 14, or
- b) an amino acid sequence consisting of at least or exactly 35 contiguous amino acid residues from SEQ ID NO:
- 14, or
- c) an amino acid sequence having a sequence identity of at least 60% with the amino acid sequence of a), or
- d) an amino acid sequence having a sequence identity of at least 60% with the amino acid sequence of b),
- said polypeptide being antigenic in a mammal.
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The method according to 18, wherein the animal is a human being.
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Dependencies are inferred from the claim text.