Sustained release hydrogel composition
AssigneeThe Governing Council of the University of Toronto
InventorsMolly SHOICHET, Michael J. COOKE, Sonja ING
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Abstract
A bioresorbable, sustained release pharmaceutical composition comprising: 1.8 wt % to 3.0 wt % methylcellulose and 0.1 wt % to 3.0 wt % hyaluronan in the form of a gel polymer matrix, and at least one local anesthetic agent, suitably ropivacaine, which may be administered by injection.
Claims15
A pharmaceutical composition comprising:
- 1.8 wt % to 3 wt % methylcellulose and 0.1 wt % to 3 wt % hyaluronan in the form of a gel polymer matrix.
6-16. (canceled)
19-28. (canceled)
A pharmaceutical composition comprising a biocompatible gel and an active ingredient wherein the active ingredient is present in a first form, which is more soluble in the biocompatible gel, and a second form, which is less soluble in the biocompatible gel, wherein in physiological conditions the first form is released from the biocompatible gel more quickly than the second form, which has a more extended release.
33-44. (canceled)
Dependencies are inferred from the claim text.