Method, device, sample analysis system for myocardial injury assessment and use thereof

A device for obtaining a characteristic parameter for assessment of myocardial injury in a subject, comprising:

• a data receiving module, configured to receive concentration data of one or more myocardial injury markers obtained from a sample from the subject, wherein the one or more myocardial injury markers comprise a large-size cardiac troponin ternary complex and/or a total cardiac troponin ternary complex;
• a data processing module, configured to process the concentration data of the one or more myocardial injury markers received by the receiving module, and obtain the characteristic parameter for assessment of myocardial injury;
• and,
• an output module, configured to output the characteristic parameter;
• wherein, the large-size cardiac troponin ternary complex is a complex formed by full-length troponin C or any fragment thereof, full-length cardiac troponin I or any fragment thereof, one or more fragments of amino acid residues 223-287 of cardiac troponin T and one or more fragments of amino acid residues 1-222 of cardiac troponin T;
• the total cardiac troponin ternary complex is a complex formed by full-length troponin C or any fragment thereof, full-length cardiac troponin I or any fragment thereof, one or more fragments of amino acid residues 223-287 of cardiac troponin T, and optionally one or more fragments of amino acid residues 1-222 of cardiac troponin T.

A sample analysis system, comprising:

• a sample carrying portion, configured to carry a container containing a sample from a subject;
• a sample dispensing portion, configured to pipette the sample from the subject from the sample carrying portion and discharge it into a reaction cup to be added with the sample;
• a reagent carrying portion, configured to carry a detection reagent;
• a reagent dispensing portion, configured to pipette the detection reagent from the reagent carrying portion and discharge it into a reaction cup to be added with the reagent;
• a reaction portion, configured to place a reaction cup so as to incubate a test solution obtained by reacting the sample from the subject with the detection reagent in the reaction cup;
• a detection portion, which has a signal detector and is configured to detect a signal of the test solution in the reaction cup to determine and output the concentration of one or more myocardial injury markers in the sample from the subject, wherein the one or more myocardial injury markers comprise a large-size cardiac troponin ternary complex and/or a total cardiac troponin ternary complex, wherein the large-size cardiac troponin ternary complex is a complex formed by full-length troponin C or any fragment thereof, full-length cardiac troponin I or any fragment thereof, one or more fragments of amino acid residues 223-287 of cardiac troponin T and one or more fragments of amino acid residues 1-222 of cardiac troponin T;
• the total cardiac troponin ternary complex is a complex formed by full-length troponin C or any fragment thereof, full-length cardiac troponin I or any fragment thereof, one or more fragments of amino acid residues 223-287 of cardiac troponin T, and optionally one or more fragments of amino acid residues 1-222 of cardiac troponin T;
• a data processing portion, which comprises a processor and a computer-readable storage medium on which the computer-readable instructions stored, characterized in that the computer-readable instructions cause the processor to implement the following steps when executed by the processor:
• receiving and processing the concentration of the one or more myocardial injury markers to obtain a characteristic parameter for assessment of myocardial injury;
• and
• outputting the characteristic parameter.