Anti-ceacam5/6 dual-binding antibodies

An antibody that binds to both CEACAM5 and CEACAM6, or an antigen binding fragment thereof, wherein the antibody comprises a heavy chain variable region (VH) and a light chain variable region (VL), and wherein

• (1) the VH comprises the HCDRs 1-3 of a VH having the amino acid sequence set forth in SEQ ID NO:
• 26, and the VL comprises the LCDRs 1-3 of a VL having the amino acid sequence set forth in SEQ ID NO:
• 27;
• (2) the VH comprises the HCDRs 1-3 of a VH having the amino acid sequence set forth in SEQ ID NO:
• 7, and the VL comprises the LCDRs 1-3 of a VL having the amino acid sequence set forth in SEQ ID NO:
• 8;
• (3) the VH comprises the HCDRs 1-3 of a VH having the amino acid sequence set forth in SEQ ID NO:
• 17, and the VL comprises the LCDRs 1-3 of a VL having the amino acid sequence set forth in SEQ ID NO:
• 18;
• or
• (4) the VH comprises the HCDRs 1-3 of a VH having the amino acid sequence set forth in SEQ ID NO:
• 31, and the VL comprises the LCDRs 1-3 of a VL having the amino acid sequence set forth in SEQ ID NO:
• 32.