Novel indenone derivatives and uses thereof

A compound of Formula 1 below or an isomer or pharmaceutically acceptable salt thereof:

• wherein, in Formula 1,
• X is a direct bond or O;
• Y is O or S;
• n is an integer from 0 to 5;
• m is an integer from 1 to 5;
• R1 is halogen, C1-6 alkyl, C6-10 aryl, —C1-6 alkyl-C6-10 aryl, or 5- or 6-membered heteroaryl, wherein the C1-6 alkyl, the C6-10 aryl, the —C1-6 alkyl-C6-10 aryl, and the 5- or 6-membered heteroaryl may each independently be unsubstituted or substituted with 1 to 4 halogens, hydroxy, CN, —NH2, —CF3, C1-6 alkyl, —C1-6 alkyl-CN, —O—C1-6 alkyl, —NH—C1-6 alkyl, or —N(C1-6 alkyl)2;
• R2 is 5- or 6-membered heteroaryl, wherein the 5- or 6-membered heteroaryl may be unsubstituted or substituted with 1 to 4 halogens, —CF3, or C1-6 alkyl;
• R3 is C6-10 aryl, 5- or 6-membered heteroaryl, or 5- to 10-membered heterocyclyl, wherein the C6-10 aryl, the 5- or 6-membered heteroaryl, and the 5- to 10-membered heterocyclyl may each independently be unsubstituted or substituted with 1 to 4 halogens, hydroxy, CN, —NH2, —CF3, C1-6 alkyl, —C1-6 alkyl-CN, —O—C1-6 alkyl, —NH—C1-6 alkyl, or —N(C1-6 alkyl)2;
• and
• the heteroaryl is an aromatic heterocycle containing 1 to 4 heteroatoms selected from N, O, and S, and the heterocyclyl is an aliphatic heterocycle containing 1 to 4 heteroatoms selected from N, O, and S.