Liquid supply and discharge device, liquid supply and discharge method, immersion objective lens system, gene sequencer, and biochemical assay method

A gene sequencer for multiple chips, wherein the gene sequencer comprises at least two chip detection positions configured to respectively install gene sequencing chips, the gene sequencer further comprises an optical system configured to detect the gene sequencing chips, the optical system comprises an objective lens movable relative to the gene sequencing chips and a liquid supply and discharge device configured to provide an immersion medium between the objective lens and the gene sequencing chip, and a side of each of the at least two gene sequencing chips close to the objective lens comprises a working surface;

• and
• wherein the liquid supply and discharge device is configured to apply the immersion medium from a liquid supply station to the working surface and the liquid supply and discharge device is movable relative to the working surface, and the liquid supply and discharge device comprises:
• at least two liquid supply conduits suspended on a side of the working surfaces to face and to be spaced apart from the working surfaces;
• at least two liquid discharge conduits spaced apart from the at least two liquid supply conduits, wherein the at least two liquid discharge conduits respectively correspond to the at least two liquid supply conduits and are suspended on the same side of the working surfaces;
• a conduit structure assembly connected between the at least two liquid supply conduits and the at least two liquid discharge conduits;
• a fluid interface assembly connected between the liquid supply station and the conduit structure assembly;
• and
• a driving assembly connected to the fluid interface assembly, wherein the driving assembly is configured to apply a forward driving force to the at least two liquid supply conduits through the fluid interface assembly so as to apply the immersion medium to the working surfaces respectively through the at least two liquid supply conduits, or to apply a reverse driving force to the at least two liquid discharge conduits so as to aspirate the immersion medium from the working surfaces.

A liquid supply and discharge method for an objective lens, wherein the objective lens is configured to detect a platform assembly comprising a plurality of platforms, each of the plurality of platforms comprises a working surface, and the liquid supply and discharge method comprises:

• a liquid supply step of suspending at least two liquid supply conduit assemblies respectively above liquid supply regions of at least two working surfaces, and applying, by using a driving assembly, a working liquid from a liquid supply station to the liquid supply regions on the at least two working surfaces through a fluid interface assembly, a conduit structure assembly and the at least two liquid supply conduit assemblies in sequence;
• a detection step of driving the objective lens to move relative to the at least two working surfaces so that the objective lens successively contacts the working liquid in the liquid supply regions on the at least two working surfaces and enters a working state, and driving the objective lens to leave the liquid supply regions after the working state ends;
• and
• a liquid discharge step of suspending a liquid discharge conduit assembly above the liquid supply regions after the objective lens leaves the liquid supply regions, and aspirating, by using the driving assembly, a fluid located in the liquid supply regions from the liquid supply regions through the liquid discharge conduit assembly, the conduit structure assembly and the fluid interface assembly in sequence.