Methods for producing functional milk proteins in a plant cell, products and uses thereof
OwnerYulia FRIDMAN, Hod YANOVERinventors
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Abstract
Provided herein are plant cells genetically modified to express at least one milk protein naturally expressed by a mammal a mammal and at least one protein promoting at least one post translation modification in said at least one milk protein, plants comprising said cells and compositions comprising said cells or any portion, or harvested product, or tissue, or isolate, or extract, or secretion, or extrudate thereof. Vectors or DNA constructs and methods for producing said genetically modified plant cells or any compositions thereof are also provided herein.
Claims21
1-56. (canceled)
A plant cell genetically modified to express at least one milk protein that is naturally expressed by a mammal and at least one kinase promoting at least one post translational phosphorylation in said expressed at least one milk protein, wherein said kinase is not FAM20C kinase.
A composition comprising at least one plant cell genetically modified to express at least one milk protein that is naturally expressed by a mammal and at least one kinase promoting at least one post translational phosphorylation in said expressed at least one milk protein, wherein said kinase is not FAM20C kinase.
A vector encoding for at least one milk protein that is naturally expressed by a mammal and at least one kinase promoting at least one post translational phosphorylation of said expressed milk protein, wherein said kinase is not FAM20C kinase.
A method of producing a composition comprising at least one plant cell genetically modified to express at least one milk protein naturally expressed by a mammal and at least one kinase promoting at least one post translational phosphorylation in said expressed at least one milk protein, the method comprising:
- a. providing at least one vector for expressing in a plant cell, at least one milk protein naturally expressed by a mammal and at least one kinase promoting at least one post translational phosphorylation in said milk protein, wherein said kinase is not FAM20C kinase;
- b. transfecting at least one plant cell with said at least one vector;
- c. providing conditions suitable for (i) expressing the at least one milk protein and the at least one kinase, and (ii) suitable for promoting said phosphorylation in said expressed milk protein.
Dependencies are inferred from the claim text.