Novel indoline derivative and use thereof
AssigneeCk Regeon Inc.
InventorsKang-Yell CHOI, Jee Sun YANG, Min-Jeong KANG, Han-Jun CHO, Sun Yong JEONG, Gyoonhee HAN, Yeji KIM
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AssigneeCk Regeon Inc.
InventorsKang-Yell CHOI, Jee Sun YANG, Min-Jeong KANG, Han-Jun CHO, Sun Yong JEONG, Gyoonhee HAN, Yeji KIM
Estimating the term…
The present disclosure relates to an indoline derivative that inhibits CXXC5-Dvl interaction, a preparation method thereof and a use thereof. The present disclosure has resolved the low solubility of a conventional indoline derivative and efficiently activates the Wnt/β-catenin signaling pathway through excellent activity by which CXXC5-Dvl interaction is inhibited, and thus can be effectively used for the effects of treating, alleviating or preventing diseases associated with CXXC5-Dvl interaction activity.
An indoline derivative represented by Chemical Formula 1, a hydrate thereof, a solvate thereof, or a pharmaceutically acceptable salt thereof:
A method for preparing an indoline derivative represented by Chemical Formula 1, comprising:
Dependencies are inferred from the claim text.