Haina polysaccharide and preparation method and use thereof, and anticoagulant drug and/or antithrombotic drug targeting intrinsic coagulation pathway

A Haina polysaccharide (HPS), wherein

• the HPS is a fucosylated chondroitin sulfate polysaccharide;
• the HPS has a weight-average molecular weight of 90,000 to 130,000, and is composed of monosaccharides comprising glucuronic acid, N-acetyl-D-galactosamine, and fucose, wherein a molar ratio of the glucuronic acid, the N-acetyl-D-galactosamine, and the fucose is in a range of 1:0.8-1.2:0.5-0.8;
• and
• a sulfate group in the HPS has a mass percentage of 25% to 40%;
• and the HPS as claimed in claim 1, wherein the HPS has a structural unit shown in formula I:
• wherein in the formula I, R1 is selected from the group consisting of H, SO3−, and fucosyl;
• R2 is selected from the group consisting of H and SO3−;
• R3 is selected from the group consisting of H and SO3−;
• R4 is selected from the group consisting of H and fucosyl;
• at least one of the R1 and the R4 is fucosyl;
• and Xe represents a cation;
• and
• the fucosyl for the R1 and the R4 has a structure shown in formula 1-1:
• wherein in the formula 1-1, R5 is selected from the group consisting of H and SO3;
• R6 is selected from the group consisting of H and SO3−;
• and Ry is selected from the group consisting of H and SO3−.