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US 2026/0242756 A1Published application
An affinity agent comprising a ligand that binds vce and comprises seq id no: 1
AssigneeRepligen Corporation
InventorsWarren Kett, Christian Ndong, Aaron Mason, Kelley Kearns, Thomas Scanlon
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Abstract
Provided herein are affinity agents comprising ligands that specifically bind target molecules. The affinity agents are useful for binding, isolation, and/or purifications.
Claims13
An affinity agent comprising a ligand that binds Vaccina Virus Capping Enzyme (VCE) wherein the ligand comprises a polypeptide having an amino acid sequence of X1QRRX2FIX3X4LRX5DPSX6SAX7LLAX8AKX9X10NDX11 (SEQ ID No:
- 1),
- wherein X1=R, G, D, W or Y;
- X2=H, S, Y, G or N;
- X3=E, W, R, G, L, T, N or Q;
- X4=A, S, D, E, L, T or V;
- X5=W, S, E, N, L or F;
- X6=D, E, N or W;
- X7=T, H, S, W, D, F or Y;
- X8=D, L or H;
- X9=S, L, I, Y, F, Q, K or N;
- X10=W, L, I, S or Y and X11=W, E, D, Q, G, R or K.
8 more elements
Dependencies are inferred from the claim text.