Fluorescence imaging reagent for lipid droplets in tissues and cells
AssigneeNational University Corporation Gunma University
InventorsToshitada YOSHIHARA, Yuhi SHIBUTA
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Abstract
An object of the present invention is to develop a fluorescent reagent capable of highly sensitive imaging of lipid droplets at levels ranging from cultured cells to individuals, which fluorescent reagent can be used in combination with a green fluorescent protein. The present invention provides a lipid droplet detection reagent including a compound represented by the following General Formula (I): wherein m represents an integer of 3 to 5; n represents an integer of 3 to 5; and R is C1-C5 alkyl, C6-C12 aryl, C7-C13 aralkyl, or hydrogen.
Claims11
A lipid droplet detection method comprising the step of:
- adding a compound represented by the following Formula (I) to a subject for detection of a lipid droplet:
- wherein
- m represents an integer of 3 to 5;
- n represents an integer of 3 to 5;
- and
- R is C1-C5 alkyl, C6-C12 aryl, C7-C13 aralkyl, or hydrogen.
(canceled)
A compound represented by the following General Formula (I)′:
- wherein
- m represents an integer of 3 to 5;
- n represents an integer of 3 to 5;
- and
- R′ is C1-C5 alkyl, C6-C12 aryl, or C7-C13 aralkyl.
Dependencies are inferred from the claim text.