Positioner system for ultrasound probe

A method comprising:

• acquiring image data of a subject using an ultrasound probe;
• identifying a region of interest based on the acquired image data;
• determining a treatment position on the skin of the subject based on the region of interest;
• positioning the ultrasound probe on or over the treatment position;
• affixing a probe holder of a positioner system over the ultrasound probe;
• rotating a first knob of the positioner system in a first direction to prevent relative motion between components of the positioner system;
• rotating a second knob of the positioner system to rotate a pivot arm of the positioner system into the subject such that the ultrasound probe is pressed against the treatment position with steady pressure;
• and
• administering a therapy dose of ultrasound energy from the ultrasound probe through the subject's skin to the region of interest.

A neuromodulation energy application system, comprising:

• an ultrasound probe configured to apply neuromodulating energy through a portion of a subject's skin to a region of interest of an internal tissue;
• and
• a positioner system comprising:
• a probe holder configured to removably couple to the ultrasound probe;
• a pressure applicator comprising a pivot arm configured to couple to the probe holder, wherein the pressure applicator is configured to rotate the pivot arm in a direction towards the subject and apply steady pressure to maintain a position of the ultrasound probe against the subject's skin;
• and
• a slider arm configured to extend near or above the subject, wherein the slider arm comprises a slide mechanism configured to couple to the pressure applicator, and wherein the slide mechanism is configured to adjust a position of the pressure applicator along a length of the slider arm.