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AssigneesThe Provost, Fellows, Scholars and Other Members of Board of Trinity College Dublin, University College Dublin, National University of Ireland, Dublin
InventorsAdrian BRACKEN, Fiona Lanigan, William Gallagher
Estimating the term…
A method for predicting risk of recurrence of cancer in an individual with cancer, the method comprising a step of assaying a cancer sample from the individual for positive expression of at least two genes or proteins encoded by those genes selected from the group consisting of FOXM1, UHRF1, PTTG1, E2F1, MYBL2, HMGB2, ATAD2, E2F8, ZNF367 and TCF19, wherein positive expression of the at least two genes correlates with increased risk of recurrence of cancer compared with an individual who does not exhibit positive expression of the at least two genes or proteins encoded by those genes.
A method of predicting risk of recurrence of cancer in an individual with cancer, the method comprising a step of assaying a cancer sample from the individual for positive expression of at least three genes, or proteins encoded by said genes, selected from FOXM1, PTTG1, ZNF367, UHRF1, E2F1, MYBL2, HMGB2, ATAD2, E2F8, and TCF19,
A method of identifying a cancer patient that is suitable for treatment with a therapy for preventing recurrence or progression of the cancer, the method comprising a step of assaying a cancer sample from the cancer patient for positive expression of at least three genes selected from:
A composition for detecting expression of at least three genes, or proteins encoded by said genes, selected from:
A method of treating breast cancer in a patient in need thereof, the method comprising:
Dependencies are inferred from the claim text.