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AssigneeUniversity of Leicester
InventorsSergey PILETSKY, Krzysztof ZALESKI, Alvaro GARCIA CRUZ, Elena PILETSKA, Michael WHITCOMBE
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The disclosure relates to a method of producing a composite particle. The method comprises contacting a catalyst particle, an oxidant and a plurality of monomers. The oxidant is a peroxide, a persulfate or ozone, and the catalyst particle is or comprises a material which possesses Fenton or Fenton-like catalytic activity. The catalyst particle catalyses the disproportionation of the oxidant to create an oxygen-radical species, which then initiates a polymerisation reaction and thereby causes the plurality of monomers to polymerise, and thereby form a polymeric shell around the catalyst particle. The invention extends to composite particles produced by the method, apparatuses comprising the composite particles and uses thereof.
A method of producing a composite particle, the method comprising contacting a catalyst particle, an oxidant and a plurality of monomers, wherein the oxidant is a peroxide, a persulfate or ozone, and the catalyst particle is or comprises a material which possesses Fenton or Fenton-like catalytic activity, such that the catalyst particle catalyses the disproportionation of the oxidant to create an oxygen-radical species, which then initiates a polymerisation reaction and thereby cause the plurality of monomers to polymerise, and thereby form a polymeric shell around the catalyst particle.
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A method of sensing a target molecule in a solution, the method comprising:
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A method of sensing a target molecule in a solution, the method comprising:
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A lateral flow sensor comprising the composite particle of claim 35.
A method of sensing a target molecule in a sample, the method comprising:
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A pharmaceutical composition comprising the composite particle of claim 35 and a pharmaceutically acceptable carrier.
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The composite particle of claim 35, wherein the composite particle comprises a drug molecule adsorbed therein and/or wherein the composite particle comprises an antibody or an aptamer conjugated to the polymeric shell, or the polymeric shell comprises an MIP, and the antibody, aptamer or MIP is configured to deliver the composite particle to a specific target.
The composite particle of claim 35, wherein the catalyst particle comprises a magnetic material.
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A sensor comprising:
A sensor comprising
A composite particle, wherein the composite particle comprises a polymeric shell around a catalyst particle.
Dependencies are inferred from the claim text.