Microspheres comprising high-dose varenicline, method for preparing same, and pharmaceutical composition comprising same

Abstract

A microsphere contains varenicline hemipamoate and a biocompatible polymer. A method of preparing the microsphere, and a pharmaceutical composition containing the microsphere are disclosed. The microsphere containing varenicline encapsulates a high concentration of varenicline, and exhibits a stable drug release rate over a long period of time and an appropriate initial release rate, and thus can maintain varenicline at an effective concentration in the blood for a certain period of time without side effects.

Dependencies are inferred from the claim text.