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US 2026/0217861 A1Published application
Antibodies for use as coagulants
AssigneeJjulius-Maximilians-UniversitäT-WüRzburg
InventorsBernhardt NIESWANDT, Sarah BECK, David STEGNER
Life of this patent
Estimating the term…
Abstract
The present invention provides novel antibodies, fragments or derivatives thereof—as well as respective (medical) uses of those compounds, such as their use as a coagulant, and/or their use in the treatment or prevention of a haemorrhagic condition.
Claims13
1-4. (canceled)
An antibody, or a functional fragment or derivative thereof, comprising:
- (i) a VH domain comprising a CDR1 having an amino acid sequence as shown in SEQ ID NO:15, a CDR2 having an amino acid sequence as shown in SEQ ID NO:16, and a CDR3 having an amino acid sequence as shown in SEQ ID NO:17, and a VL domain comprising a CDR1 having an amino acid sequence in accordance with the amino acid sequence as shown in SEQ ID NO:18, a CDR2 having an amino acid sequence in accordance with the amino acid sequence as shown in SEQ ID NO:19, and a CDR3 having an amino acid sequence in accordance with the amino acid sequence as shown in SEQ ID NO:20;
- (ii) a VH domain comprising a CDR1 having an amino acid sequence as shown in SEQ ID NO:1, a CDR2 having an amino acid sequence as shown in SEQ ID NO:2, and a CDR3 having an amino acid sequence as shown in SEQ ID NO:3, and a VL domain comprising a CDR1 having an amino acid sequence in accordance with the amino acid sequence as shown in SEQ ID NO:4, a CDR2 having an amino acid sequence in accordance with the amino acid sequence as shown in SEQ ID NO:5, and a CDR3 having an amino acid sequence in accordance with the amino acid sequence as shown in SEQ ID NO:6.
7-8. (canceled)
11-15. (canceled)
Dependencies are inferred from the claim text.