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US 2026/0217851 A1Published application
Compositions that Target CD138 and CD3 and Methods of Making and Using the Same
AssigneeThe Medical College of Wisconsin, Inc.
InventorsCharles E. Hay, Jeffrey A. Medin
Life of this patent
Estimating the term…
Abstract
Disclosed are bispecific single-chain constructs, pharmaceutical compositions comprising the constructs, methods of treatment using the pharmaceutical compositions, polynucleotides encoding the constructs, and methods of making the constructs.
Claims25
A bispecific single-chain polypeptide construct comprising an anti-CD138 domain and an anti-CD3 domain, wherein the anti-CD138 domain comprises SEQ ID NO:
- 1 or a sequence with at least 85% identity to SEQ ID NO:
- 1.
10-12. (canceled)
15-16. (canceled)
(canceled)
25-30. (canceled)
33-36. (canceled)
Dependencies are inferred from the claim text.