System and method for purification of immunoglobulins from a biological sample

A device for automatic purification and concentration of immunoglobulins from a blood plasma sample, the device comprising:

• one or more pumps;
• one or more valves;
• and
• a plurality of connecting elements configured to hold corresponding buffer vessels and/or bio-process vessels,
• wherein, when said plasma sample is introduced to the device, a sequential purification process is facilitated, whereby plasma sample fractions are transferred between one or more of the bio-process vessels, such that immunoglobulins are purified, concentrated and collected at a collecting vessel, wherein the transferring of the fractions is facilitated by a coordinated operation of the one or more pumps and the one or more valves.

A sterile kit for automatic purification and concentration of immunoglobulins from blood plasma sample, the kit comprising:

• a plurality of reagent vessels, comprising one or more mixtures for use during the purification process;
• a plurality of bio-process vessels, configured to facilitate purification steps;
• one or more filtration units;
• and
• one or more separation columns;
• wherein the kit is configured to associate with a corresponding separation device, to allow sequential transfer of plasma sample fractions between the bio-process vessels, one or more filtration units and/or the one or more separation columns, to result in purified concentration immunoglobulin composition, collected at a collection vessel.