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US 2026/0216403 A1Published application
Drug delivery system and methods of using the same
AssigneeAxogen Corporation
InventorsKasra TAJDARAN, Justin DEUERLING, Angelo SCOPELIANOS, Robert C. DILUCCIO
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Abstract
A method of preparing an implantable biomaterial includes combining a polymer comprising polydioxanone with a neuro-regenerative agent or an immunosuppressive agent comprising at least one immunophilin ligand, and melting the polymer. The method further includes extruding the combined polymer and the neuro-regenerative agent or immunosuppressive agent to form the implantable biomaterial.
Claims20
A method of preparing an implantable biomaterial, comprising:
- combining a polymer comprising polydioxanone with a neuro-regenerative agent or an immunosuppressive agent comprising at least one immunophilin ligand;
- melting the polymer;
- and
- extruding the combined polymer and the neuro-regenerative agent or the immunosuppressive agent to form the implantable biomaterial.
1 more element
A method of preparing an implantable biomaterial, comprising:
- combining a polymer and FK506;
- melting the polymer;
- and
- extruding the combined polymer and FK506 to form the implantable biomaterial.
1 more element
An implant, comprising:
- a biomaterial, wherein the biomaterial comprises:
- a polymer;
- and
- FK506 combined with the polymer;
- wherein the biomaterial is incorporated within the nerve implant in the form of one or more extruded pellets, rods, sheets, springs, or fibers.
2 more elements
Dependencies are inferred from the claim text.